Technical Details of NEXTERION® glass substrates
NEXTERION® takes pride in offering a comprehensive array of options tailored to meet your specific needs. From structuring and bonding techniques to a diverse range of thicknesses and dimensions, our products are designed to provide unparalleled flexibility and customization. Additionally, we offer a variety of coating options to enhance performance and functionality, ensuring that every substrate meets the rigorous demands of your application. Discover the perfect combination of technical excellence and adaptability for your project.
Structuring and bonding
SCHOTT MINIFAB has an innovative portfolio of structured glass substrates, produced in-house, that offers highly accurate and versatile features. Using an ultra-short pulse laser technology, structuring design can be tailor to exact specifications.
Also available is a unique pre-scoring process, which enables small chip sizes. Standard sized glass substrates get pre-scored in the required chip size for further processing into a larger format and then separated into the final format at the end of processing chain.
Substrates can be delivered in the pre-scored version and separated for our customers.
General structuring
| Parameters for BOROFLOAT® 33, D 263® * |
Unit |
Value |
|---|---|---|
|
Thickness range |
mm |
0.1 - 3.0 |
|
Maximum Format |
mm |
200 |
|
Min. structuring radius |
µm |
150 |
* Other materials upon request
Pre-Scoring
|
Parameters |
Unit |
Value |
|
|---|---|---|---|
|
Standard formats* |
Wafer |
mm |
148 x 148 |
|
Microtiter plate |
mm |
110 x 74 |
|
|
Slide |
mm |
75.6 x 25 |
|
|
Edge roughness |
Ra |
µm |
< 1 |
|
Min. chip size ** |
|
µm |
20 (theoretical) |
* Customized formats upon request
** strongly depending on thickness
In addition we offer bonded products combining glass/glass or glass/tape materials used in applications which require a structuring inside the substrate or chip. Bonded substrates are especially interesting for microfluidic applications like NGS, molecular diagnostics and life science research.
Tape Bonding
|
Parameters |
Unit |
Value |
|---|---|---|
|
Inlet / Outlet hole diameter |
µm |
< 500 |
|
Channel width |
µm |
200 |
|
Channel depth |
µm |
45 - 80 |
|
Distance between sturctures |
µm |
up to 200 |
Fusin Bonding
|
Structuring |
Interposer Channel |
Laser-abiated Channel |
||
|---|---|---|---|---|
|
|
Unit |
Value |
Unit |
Value |
|
Inlet / Outlet hole diameter |
mm |
0.5 - 2 |
mm |
0.5 - 2 |
|
Taper angle hole |
° |
< 3 |
° |
< 3 |
|
Channel width |
µm |
> 500 |
µm |
> 20 |
|
Channel depth |
mm |
0.1 - 2.25 |
µm |
10 - 100 |
|
Channel length |
mm |
< 130 |
mm |
< 42 |
|
Taper angle channel |
° |
< 3 |
° |
70 |
|
Distance between sturctures |
mm |
> 1 |
µm |
20 |
|
Distance edge to channel |
mm |
> 5 |
mm |
> 5 |
Coating
SCHOTT MINIFAB has in-house capabilities for a variety of functional coatings.
- Dip coating
- Chemical vapor deposition (CVD)
- Sputter deposition
- Solvent-based reactor method
- Spin coating
Beside standard functional coatings, scale manufacture of customer-developed coatings can be offered.
The below table provides an overview which of the SCHOTT MINIFAB coatings may be appropriate for your application.
| Probe type | Coating |
|---|---|
| Oligonucleotides | Aminosilane | Epoxysilane | 3-D Hydrogel | 3-D Polymer | Poly-L-Lysine |
| cDNA / PCR | Aminosilane | Epoxysilane | Aldehydesilane| Poly-L-Lysine |
| Peptides | Epoxysilane | Aldehydesilane |
| Proteins | 3-D Hydrogel | 3-D Polymer |
| Antibodies | Epoxysilane | Aldehydesilane | 3-D Hydrogel | 3-D Polymer |
| Glycans | 3-D Hydrogel | 3-D Polymer |
| Cells / Tissues | Depending on type of cell / tissue, please contact us for support and free-of-charge evaluation samples |
| Biotin modified molecules | Streptavidin |
| Bacterial artificial chromosomes (BAC) | Aminosilane | Epoxysilane | Aldehydesilane | Poly-L-Lysine |
| P1 artificial chromosomes (PAC) | Aminosilane | Epoxysilane | Poly-L-Lysine |
| Yeast artificial chromosomes (YAC) | Aminosilane | Epoxysilane | Aldehydesilane | Poly-L-Lysine |
SCHOTT MINIFAB also offers microarray printing expertise.
Material and dimensions
Comparison of SCHOTT MINIFAB standard glass substrate properties:
|
Property |
Unit |
BOROFLOAT® 33 |
D 263® |
||
|---|---|---|---|---|---|
|
Mechanical propertiy |
Density (annealed at 40 °C/h) |
ρ |
g/cm3 |
2,20 |
2.51 |
|
Thermal properties |
Cofficient of thermal expansion |
CTE α (20-300 °C) |
10-6/K |
3,25 |
7.20 |
|
Transformation temperature |
Tg |
°C |
525 |
557 |
|
|
Optical properties |
Refractive index (thickness = 0.70 mm) |
րe |
- |
1.47311 |
1.5255 |
|
րd |
- |
1.47140 |
1.5231 |
||
|
Abbe value |
νe |
|
55 |
55 |
|
|
Dispersion |
րF-րC |
10-4 |
71,9 |
96,0 |
|
|
Transmittance (thickness = 0.30 mm) |
τ (λ254) |
% |
< 0.1 |
< 0.1 |
|
|
τ (λ380) |
% |
91.2 |
91.2 |
||
|
τ (λ632.8) |
% |
92.0 |
92.0 |
||
|
τ (λ1064) |
% |
92.0 |
92.0 |
||
|
Luminous transmittance (thickness = 1.1 mm) |
τ(λvD65) |
% |
92.7 |
91.7 |
|
|
Stress optical coefficient |
C |
1.02·10-12 m2/N |
4.0 |
3.4 |
|
|
Chemical properties |
Hydrolytic resistance (DIN ISO 719) |
Class HGB 1 |
|
||
|
Acid resistance (DIN 12116) |
Class S 4 |
|
|||
|
Alkali resistance (DIN ISO 695) |
Class A 3 |
|
|||
The range of glass thicknesses available is very wide depending on the glass type. Typically used glass substrates (BOROFLOAT® 33 and D263®) are borosilicate glass. Other glass types are possible upon request.
Thicknesses and dimensions
|
Type |
Product size [mm] |
Thickness [mm] |
Pieces per pack |
|---|---|---|---|
|
Side glass |
75.6 x 25.0 |
1.0 |
25 |
|
Plate glass |
110.0 x 74.0 |
1.0 |
5 |
|
Customized dimensions |
up to 200 |
0.1 - 3.0 |
variable |
Marking
SCHOTT MINIFAB has in-house capability for laser micromachining of glass. All substrates can be customized with markings including logos, barcodes, fiducial marks and graphics that are robust enough to withstand challenging biomedical laboratory procedures. These markings can be added at any location on or within the glass surface.
Our key capabilities include: laser-induced particle transfer, hydrophobic ink, laser ablation, laser-induced internal marking.
| Parameters | Specification | |
|---|---|---|
| Barcode type |
Standard | 1D: Code 128 |
| Custom | 1D: Code 128 a/b/c; Code 39; 2/5-Family | |
| 2D: QR Code, Data Matrix Code | ||
| Graphics & fiducials | Resolution | 127 dpi (binary images) |
| Line width | 20 µm (vector format) | |
| Size max. | 40 mm x 40 mm | |
| Barcode & text | Hight min. | 0.12 mm |
| 2D code min. | 1.6 mm (others on request) | |
| Distance to the edge | min. 1 mm | |
Want to know more? Let's talk
Whether you need more information, samples, a quote, or advice for a project, I would be delighted to talk to you.
