Product Variants of NEXTERION® glass substrates

To cater to the demand for customized products, we specialize in the development of distinctive formats, materials, coatings, structuring and bonding solutions. Leveraging our stringent quality standards and efficient volume production methods, we empower our customers to achieve consistently reproducible results, addressing the evolving challenges of diagnostic and life science endeavors.

Bonded

NEXTERION® bonded glass substrates

NEXTERION® bonded products are used in applications which requires a structuring inside the substrate or chip. Bonded substrates are especially interesting for microfluidic applications like NGS, molecular diagnostics and life science research. We offer different options for channel creation. Channels can either be formed via tape or by structured glass.
NEXTERION® bonded glass substrates
NEXTERION® bonded glass substrates
NEXTERION® bonded glass substrates
NEXTERION® bonded glass substrates
  • NEXTERION® bonded glass substrates
  • NEXTERION® bonded glass substrates
  • NEXTERION® bonded glass substrates
  • NEXTERION® bonded glass substrates

CHARACTERISTICS

  1. Tape Bonding
    For all NEXTERION® taped-bonded products the channels are formed via adhesive tape. The channel depth is defined by tape thickness. The bonding process takes place at room temperature. This allows an optional functional coating on either top or bottom plate.

  2. Fusion bonding
    All NEXTERION® fusion-bonded products are fully glass-based systems either in two or in three layer-designs. The layers are aligned and directly bonded via pressure contacting. The fusion bonding occurs at high temperatures (~ 500 - 600 °C). SCHOTT MINIFAB offers fully glass-based systems either in two or three layer-design. The layers are aligned either via wet (water) or via direct pressure contacting.


YOUR ADVANTAGES

Manufacturing takes place in ISO class 5 environment, all relevant processes are in place for diagnostic company needs. In the following an overview of the available bonding methods including design options.

Structured

NEXTERION® structured glass substrates

The glass structuring at SCHOTT MINIFAB is a laser-based process. This way we are able to offer maximal design flexibility and high geometric precision. The innovative approach of laser-based structuring in combination with our unique glass bonding technology is a cost-efficient solution for manufacturing microfluidic systems, including lab-on-a-chip consumables and flow cells. This method enables flexible structuring with smooth edges, allowing precise creation of flow cell channels and customizable chip sizes from high-quality glass substrates. With NEXTERION® PreScora, we provide pre-scored substrates that can be easily separated at any stage of the process, ensuring robust solutions for demanding applications in the growing biochip market.
NEXTERION® structured glass substrates
NEXTERION® structured glass substrates
NEXTERION® structured glass substrates
  • NEXTERION® structured glass substrates
  • NEXTERION® structured glass substrates
  • NEXTERION® structured glass substrates

CHARACTERISTICS

1. Material

The standard glass types used for NEXTERION® glass substrates are our borosilicate glass types BOROFLOAT® or D 263®. If needed, we can also offer other options selected from the wide range of SCHOTT specialty glass materials.

 

2. 3-D structures

To maximize our customizability, we use multi-layer designs to create 3-D structures in glass. Structures will either be created by laser-ablation or by stacking of structured layers. This technology can also be combined with adhesive tape layers. The thickness of the layers ranges from 0.07 mm to 2 mm.

 

3. PreScora

The growing complexity of the consumable biochip market is driving demanding applications. Very often the further processing on wafer level is required. For diagnostic products final separation into chips, using conventional dicing processes bare a high risk of contamination. To solve this problem, we are offering pre-scored substrates that are scribed into the final chip size to be separated into the requested format at the needed step of the process chain without dicing.

 

YOUR ADVANTAGES

  • Complete solutions for biochips
  • Fast high-quality prototyping
  • No masking required for 3-D structuring
  • Flexible and high precision structuring
  • High-performance diagnostic-quality glass substrates 
  • Available with additional organic and/or inorganic coatings
  • Available with markings or barcodes
  • Competitive pricing for glass biochips
  • ISO class 5 clean room production
  • ISO 19001 and 13485 certified
Coated

NEXTERION® coated glass substrates

We offer a wide range of organic and inorganic coating chemistries for life-science and diagnostics. This includes coatings on flat glass substrates, 3D geometries and/or coating of microfluidic channels.
NEXTERION® coated glass substrates

CHARACTERISTICS

1. Organic coatings

Featuring a various assortment of coating technologies, e.g. dip coating, chemical vapor deposition (CVD), solvent-based reactor method, spin coating we are offering a portfolio of standard coatings as well as customized coatings. Customization may either be the development of specific coatings for a special application or the process transfer of an already established coating. Our production facilities are equipped to meet your manufacturing needs from early prototyping to serial production. 

Standard organic coatings:

  • Aldehydesilane Coating

  • Aminosilane Coating

  • Epoxysilane Coating

  • Poly-L-Lysine Coating

  • Streptavidin Coating

  • 3-D Hydrogel Coating

  • 3-D Polymer Coating

 

2. Inorganic coatings

Offering a diverse selection of available coating materials, applied by physical vapor deposition (PVD), atomic layer deposition (ALD), RF and reactive sputtering, we are equipped to develop and optimize your specific coating process and scale manufacturing. To provide maximal customization, we are able to structure the coating by masking or in post processing.

Examples of inorganic coatings:

  • Metallic Coatings, e.g. Copper, Aluminum, Silver, Gold, Chrome, Nickel, Titanium

  • Oxidic Coatings, e.g. Silicon Oxide, Alumina, Chromium Oxide, etc.

  • Cermet Coatings, e.g. Black Chrome, Aluminum/Alumina

  • Transparent conductive materials, e.g. ITO

  • Customized Coating

 

YOUR ADVANTAGES

  • Wide range of organic and inorganic coatings
  • Structuring of coatings
  • Option of double-sided sputtering
  • Combination of different coating options
  • Reliable and homogeneous coating
  • Flexibility in glass material and dimensions
  • Available with markings or barcodes
  • High batch quantity
  • ISO class 5 clean room production
  • ISO 19001 and 13485 certified
Uncoated

NEXTERION® uncoated glass substrates

Standard glass substrates used at SCHOTT MINIFAB are BOROFLOAT® 33 and D 263®. Both materials are borosilicate glasses with high chemical resistance, excellent transmission, low fluorescence, and exceptional flatness. In case special materials or material properties are requested please contact us to find an appropriate material out of the wide range of SCHOTT‘s specialty glass materials.
NEXTERION® uncoated glass substrates

YOUR ADVANTAGES

BOROFLOAT® 33 and  D 263® are produced with the purest raw materials and manufactured with stringent quality controls systems.  The manufacturing process results in a pristine, fire-polished surface, making it the perfect material for diagnostics and life science research.  The uncoated glass material types are cleaned in an ISO class 5 cleanroom and offered in standard and custom formats, to meet tolerances and technical specifications.

 

Want to know more? Let's talk

Whether you need more information, samples, a quote, or advice for a project, I would be delighted to talk to you.

Karola Koban

Karola Koban

SCHOTT MINIFAB overview

Discover the full capabilities of SCHOTT MINIFAB