SCHOTT TOPPAC® sensitive

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64 Pieces/Tub

Product description
Technical details

Prefillable COC syringes for sensitive drugs

SCHOTT TOPPAC® sensitive syringes are designed to keep biologics and other sensitive drugs stable, reducing contaminations that could impact the drug stability such as E&L, free radicals, free silicone oil and sub-visual particles. Made from a break-resistant and lightweight COC material, TOPPAC® sensitive syringes offer excellent barrier properties, no ion or heavy metal release and low protein adsorption to increase drug shelf life.

A key advantage of these advanced glass-like syringes is the low material-impacted sterilization methods EtO- and steam sterilization, the use of newest and cleanest rubber formulations as well as a reactive siliconization process to reduce free silicone oil and sub-visual particles.

Properties

Designed for the storage and delivery of biologics and other sensitive drugs.
Reduces drug contamination for increased shelf life and patient safety.
Made using an advanced Cyclic Olefin Copolymer (COC) material, which is inert and stable for a broad range of solutions.
Sterilized using Ethylene Oxide (EtO) to reduce free radicals and extractables.
Manufactured using cross-linked silicone for lower free silicone and reduced silicone droplets.
Tip cap and plunger made from steam-sterilized, pure rubber formulations.

Chemical Resistance

• The advanced COC material used in SCHOTT TOPPAC® sensitive syringes is inert and stable for a broad range of solutions.
• COC material exhibits excellent barrier properties for water vapor and oxygen permeability, leading to longer drug shelf life.
• No ion or metal release.
• Made using pure elastomeric components for reduced particle load and chemical extractables.
• COC material manufactured in accordance with EP, JP, and USP class VI (DMF 12132) standards.
• Supported by extractable studies, as well as biocompatibility studies.
• Extremely low sub visual particle load: compliant with USP 789

• Syringe material made from inert COC material with no ion or heavy metal release and excellent barrier properties.
• Made using pure elastomeric components for reduced particle load and chemical extractables.
• Exhibits an extremely low sub visual particle load, compliant with the international standard USP 789.
• Manufactured using cross-linked silicone for lower free silicone and reduced silicone droplets.

Dimensions & Cosmetics

• SCHOTT TOPPAC® sensitive syringes are available in a range of volumes from 1-10 ml.
• The syringes are lightweight, with a glass-like appearance.
• Injection molding of the syringe barrel allows for small tolerances and very little dead space.
• Very low quantity of free silicone, which enables gliding forces to remain constant over time.

Possible Applications

Biologics
Since SCHOTT TOPPAC® sensitive syringes offer high levels of stability and barrier properties, biologics and other sensitive drugs remain safe for longer, increasing safety and reducing costs.
Ophthalmics
Storing and administering medication to the eye requires syringes that can not only keep highly sensitive drugs stable, but deliver very low volume drugs accurately. SCHOTT TOPPAC® sensitive answers these challenges.
WFI
SCHOTT TOPPAC® sensitive syringes are ideal for water-for-injection (WFI) applications, since they offer excellent barrier properties for water vapor and oxygen permeability.

Advantages

• SCHOTT TOPPAC® sensitive syringes are made from the highest quality COC material, which is inert and stable for a broad range of highly sensitive solutions.
• Syringes are delivered in ready-to-use packages with volumes ranging from 1-10 ml.
• SCHOTT provides a one-stop-shop for syringes and a broad range of compatible components.
• SCHOTT TOPPAC® sensitive syringes have the highest quality standards, with extremely low sub visual particle load.
• SCHOTT has a proven track record in pharmaceutical packaging and is registered in more than 90 countries.
• Our syringes are manufactured in accordance with EP, JP, and USP class VI (DMF 12132) standards.
• Manufacturing process is validated and documented by the US FDA and China NMPA regulatory bodies.

SCHOTT Pharma Online Shop.

Our Online Shop provides an easy and fast access to small volume and high quality pharmaceutical packaging solutions. With standardized and pre-tested products we ensure fast delivery times. Our customer care helps you in case you need a product recommendation to safely package your drug.

Open at all times. Quality at all times.